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中文小鼠
Ercc4 - excision repair cross-complementing rodent repair deficiency, complementation group 4
Alias:
Xpf
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这个基因编码一个蛋白质，具有激活TFIID类转录因子复合物结合活性和特异性结合启动子的能力它在DNA修复、紫外线保护和自噬调控的上游发挥作用该基因位于染色体端区，位于细胞核中它被认为是ERCC4-ERCC1复合物和核酸切除修复因子1复合物的一部分该基因在中枢神经系统和视网膜中表达它被用于研究F型色素性皮肤病这个基因的人类同源物与Fanconi贫血补充分组Q、XFE早老症综合征、胰腺癌、色素性皮肤病和F型色素性皮肤病有关这个基因与人类ERCC4（ERCC切除修复4，内切酶催化亚基）具有同源性
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Ercc4 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
