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中文人类
PLA2G3 - Phospholipase A2 Group III
Alias:
SPLA2III
sPLA2-III
GIII-SPLA2
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这个基因编码一个属于可分泌磷脂酶A2家族的蛋白质，其成员包括蜜蜂毒液酶。编码的酶在脂质代谢中发挥作用，并催化磷脂的sn-2酰基键的钙依赖性水解，以释放花生四烯酸和溶血磷脂酸。该酶作为纤毛生成的负调控因子，可能通过刺激肿瘤细胞生长和血管生成在癌症发展中发挥作用。这个基因与氧化应激有关，这个基因中的多态性与阿尔茨海默病的风险相关。[由RefSeq，2014年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PLA2G3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
