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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PA2G4 - Proliferation-associated 2G4
Alias:
EBP1
HG4-1
ITAF45
p38-2G4
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种参与生长调控的RNA结合蛋白。这种蛋白存在于前核蛋白体核糖核酸蛋白复合体中,可能参与核糖体的组装和rRNA加工的中期和晚期步骤的调控。这种蛋白可以与ErbB3受体的胞质结构域相互作用,并可能有助于传递生长调控信号。这种蛋白还是雄激素受体调控基因和其他细胞周期调控基因的转录共同抑制子,通过与其中的组蛋白去乙酰化酶相互作用。这种蛋白已被证明参与生长抑制和人类癌细胞系的分化诱导。在染色体3、6、9、18、20和X上已经发现了六个假基因。[由RefSeq,2008年7月提供]
Related ID:
NCBI:5036
ENSEMBL:ENSG00000170515
HGNC:8550
UNIPROT:Q9UQ80
OMIM:602145
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5036
1
13
9352 bp
43.79
1
--
5
27
PA2G4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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