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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
P2RY2 - Purinergic Receptor P2Y2
Alias:
P2U
HP2U
P2U1
P2UR
P2Y2
P2RU1
P2Y2R
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因的产物属于P2受体家族,该家族由细胞外核苷酸激活并细分为P2X配体门控离子通道和P2Y G蛋白耦合受体。这个家族具有几种具有不同药理学选择性的受体亚型,这些亚型在某些情况下重叠,针对各种腺苷和尿苷核苷酸。这种受体存在于许多细胞类型中,由ATP和UTP激活,据报道在某些癌细胞类型中过度表达。它参与许多细胞功能,如增殖、凋亡和炎症。已发现该基因的三个转录变异体编码相同的蛋白质。[由RefSeq,2013年3月提供]
Related ID:
NCBI:5029
ENSEMBL:ENSG00000175591
HGNC:8541
UNIPROT:P41231
OMIM:600041
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5029
3
3
24147 bp
42.27
24
--
7
5
P2RY2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Status
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References Literature
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