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中文人类
P2RX7 - Purinergic Receptor P2X 7
Alias:
P2X7
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这个基因的产物属于ATP的嘌呤受体家族。这个受体作为配体门控离子通道发挥作用，并通过形成对大分子通透的膜孔负责ATP依赖的巨噬细胞溶解。细胞质中ATP激活这个核受体可能是细胞活性与基因表达变化耦合的一种机制。已经识别出多种可变剪接变异体，其中大多数符合无义介导的衰减（NMD）标准。[由RefSeq，2010年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
P2RX7 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
