大鼠

Cbl - Cbl proto-oncogene

Alias:
c-Cbl
RGD1561386
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
使多个功能成为可能,包括SH3结构域结合活性;磷脂酰肌醇3-激酶调节亚单位结合活性;和泛素蛋白酶活性。参与多个过程,包括细胞对生长因子刺激的响应;细胞对缺氧-葡萄糖剥夺的响应;和蛋白质泛素化。位于几个细胞组件中,包括生长锥;膜筏;和细胞质核周区域。与粘着斑共定位。用于研究短暂的大脑缺血。先天性膈疝、高血糖和1型糖尿病的生物标志物。该基因的人类同源物涉及急性髓细胞白血病;幼年粒细胞-单核细胞白血病;非小细胞肺癌;和髓样肿瘤。与人类CBL(Cbl原癌基因)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
16
83797 bp
Unknown
15
1

Cbl Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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