人类

OSM - Oncostatin M

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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码白血病抑制因子/巨细胞刺激素-M(LIF/OSM)家族的一员。编码的前原蛋白在蛋白水解过程中被加工成成熟蛋白。这种蛋白质是一种分泌型细胞因子和生长调节剂,可抑制多种肿瘤细胞系的增殖。该蛋白质还调节其他细胞因子的产生,包括内皮细胞中的白细胞介素6、粒细胞-集落刺激因子和粒细胞-巨噬细胞集落刺激因子。这个基因和相关基因,即也在染色体22上存在的白血病抑制因子,可能源于一个共同祖先基因的复制。可变剪接导致多个转录变异体,至少其中一个编码经蛋白水解加工的异构体。[由RefSeq,2016年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
3
4023 bp
28.48
24
--
6
12

OSM Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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