Ldlrap1 - low density lipoprotein receptor adaptor protein 1

Predicted to enable several functions, including AP-1 adaptor complex binding activity; AP-2 adaptor complex binding activity; and amyloid-beta binding activity. Predicted to be involved in several processes, including low-density lipoprotein particle clearance; positive regulation of low-density lipoprotein particle clearance; and receptor-mediated endocytosis. Predicted to act upstream of or within cholesterol homeostasis. Located in axon. Human ortholog(s) of this gene implicated in autosomal recessive hypercholesterolemia. Orthologous to human LDLRAP1 (low density lipoprotein receptor adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]