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中文大鼠
En2 - engrailed homeobox 2
Alias:
RGD1561842
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预测能够使DNA结合的转录因子活性增强，特异性地与RNA聚合酶II结合，并具有序列特异性的DNA结合活性。参与多个过程，包括胚胎大脑发育；神经元凋亡过程的负调控；以及RNA聚合酶II驱动的转录调控。在神经系统发育的上游或内部发挥作用，并正向调控RNA聚合酶II驱动的转录。位于细胞膜和细胞核中。该基因的人类同源物与自闭症障碍有关。与人类的EN2（engrailed homeobox 2）正交。[由基因组资源联盟，2022年4月提供]
Related ID：
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
En2 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
