Involved in positive regulation of NIK/NF-kappaB signaling. Used to study hypohidrotic ectodermal dysplasia and otitis media. Human ortholog(s) of this gene implicated in ectodermal dysplasia 11A and ectodermal dysplasia 11B. Orthologous to human EDARADD (EDAR associated death domain). [provided by Alliance of Genome Resources, Apr 2022]