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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TNFRSF11B - TNF Receptor Superfamily Member 11b
Alias:
OPG
TR1
OCIF
PDB5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是TNF受体超家族的一员。这种蛋白质是成骨细胞分泌的诱饵受体,作为骨吸收的负调控因子。这种蛋白质特异性地与其配体骨保护蛋白配体结合,两者都是破骨细胞发育的关键细胞外调控因子。研究小鼠对应物也表明,这种蛋白质及其配体在淋巴结器官发生和血管钙化中发挥作用。已经报道了这个基因的可变剪接转录变异体,但其完整的长度尚未确定。[由RefSeq,2008年7月提供]
Related ID:
NCBI:4982
ENSEMBL:ENSG00000164761
HGNC:11909
UNIPROT:O00300
OMIM:602643
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4982
1
5
28329 bp
46.03
146
3
8
15
TNFRSF11B Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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References Literature
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