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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
OPCML - Opioid Binding Protein/cell Adhesion Molecule Like
Alias:
OPCM
OBCAM
IGLON1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码免疫球蛋白超家族中的IgLON亚家族成员。编码的前原蛋白在蛋白水解过程中被加工成成熟蛋白。这种蛋白位于质膜上,可能对阿片受体功能具有辅助作用。这个基因在大鼠和牛中有一个直向同源基因。由大鼠基因编码的阿片结合细胞粘附分子在存在酸性脂质时会结合阿片碱,对mu样物质具有选择性,并作为GPI锚定的蛋白发挥作用。由于在进化过程中,编码的蛋白在物种间高度保守,它可能在哺乳动物系统中具有基本作用。可变剪接导致多个转录变异体,至少其中一个编码被蛋白水解加工的异构体。[由RefSeq,2016年1月提供]
Related ID:
NCBI:4978
ENSEMBL:ENSG00000183715
HGNC:8143
UNIPROT:Q14982
OMIM:600632
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4978
8
8
1117521 bp
38.01
9
1
8
7
OPCML Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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Protein
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* This data comes from NCBI.
Gene Expression
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Name
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Status
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Link
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References Literature
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