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中文人类
ATP2B4 - ATPase Plasma Membrane Ca2+ Transporting 4
Alias:
MXRA1
PMCA4
ATP2B2
PMCA4b
PMCA4x
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这个基因编码的蛋白质属于在反应周期中形成天冬氨酸磷酸盐中间体的P型初级离子转运ATP酶家族。这些酶从真核细胞中去除二价钙离子，并在细胞内钙稳态中发挥关键作用。哺乳动物血浆膜钙ATP酶同源物由至少四个单独的基因编码，这些酶的多样性进一步通过转录本的替代剪接增加。不同同源物和剪接变体的表达在发育、组织和细胞类型特异性地调节，这表明这些泵在特定细胞和组织的生理需求上具有功能性适应性。这个基因编码血浆膜钙ATP酶同源物4。已识别出编码不同同源物的可变剪接转录本。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ATP2B4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
