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中文人类
ROR1 - Receptor Tyrosine Kinase Like Orphan Receptor 1
Alias:
NTRKR1
dJ537F10.1
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这个基因编码一个类似于酪氨酸激酶的孤儿受体，可调节中枢神经系统的神经突生长。编码的蛋白质是一种糖基化的I型膜蛋白，属于细胞表面受体的ROR亚家族。它是一种伪激酶，缺乏催化活性，可能与非典型Wnt信号通路相互作用。这个基因在胚胎早期发育过程中高度表达，但在成年组织中表达水平非常低。这个基因的过度表达与B细胞慢性淋巴细胞白血病有关。可变剪接导致多个转录变异体，编码不同的异构体。[RefSeq，2012年6月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ROR1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
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Regulation
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References Literature
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