Log In|Sign Up
中文人类
NTRK2 - Neurotrophic Receptor Tyrosine Kinase 2
Alias:
OBHD
TRKB
DEE58
trk-B
EIEE58
GP145-TrkB
加入收藏
这个基因编码神经生长素酪氨酸激酶(NTRK)家族的成员。这个激酶是一个膜结合受体，在神经生长因子结合后，自身磷酸化并激活MAPK信号通路。通过这个激酶的信号传导导致细胞分化。这个基因的突变与肥胖和情绪障碍有关。可变剪接产生了多种转录子变异体。[RefSeq,2014年5月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NTRK2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
