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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
NRGN - Neurogranin
Alias:
RC3
hng
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
神经颗粒素(NRGN)是神经元特异性的大鼠RC3/神经颗粒素基因的人类同源物。该基因编码一种在缺乏钙离子的情况下与钙调素结合的突触后蛋白激酶底物。NRGN基因包含四个外显子和三个内含子。外显子1和2编码蛋白质,外显子3和4包含非翻译序列。研究表明,NRGN是人脑中甲状腺激素的直接靶标,并且该基因表达的控制可能在发育过程中以及成年受试者中甲状腺功能减退对精神状态的许多后果中起到基础作用。[由RefSeq,2008年7月提供]
Related ID:
NCBI:4900
ENSEMBL:ENSG00000154146
HGNC:8000
UNIPROT:Q92686
OMIM:602350
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4900
2
4
7269 bp
7.62
3
--
7
9
NRGN Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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