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中文人类
ATP2B1 - ATPase Plasma Membrane Ca2+ Transporting 1
Alias:
MRD66
PMCA1
PMCA1kb
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这个基因编码的蛋白质属于P型初级离子转运ATP酶家族，在反应循环中，会形成天冬氨酸磷酸中间物。这些酶在真核细胞中克服非常大的浓度梯度去除二价钙离子，并在细胞内钙稳态中起到关键作用。哺乳动物的质膜钙ATP酶同种型由至少四个独立基因编码，这些酶的多样性通过转录本的替代剪接进一步增加。不同同种型和剪接变体的表达受发育、组织和细胞类型特异性的调控，表明这些泵功能上适应特定细胞和组织的生理需求。这个基因编码质膜钙ATP酶同种型1。已经发现了编码不同同种型的替代剪接转录变异体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ATP2B1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
