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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
NRCAM - Neuronal Cell Adhesion Molecule
Alias:
NEDNMS
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
细胞粘附分子(CAMs)是免疫球蛋白超家族的成员。这个基因编码一个具有多个免疫球蛋白样C2型结构域和纤连蛋白型-III结构域的神经元细胞粘附分子。这个锚蛋白结合蛋白参与神经元-神经元的粘附,并在轴突锥形生长过程中促进定向信号传递。这个基因也在非神经元组织中表达,并通过其细胞内结构域到细胞骨架的定向细胞迁移过程中的信号传递,可能在细胞间通信中扮演一般性角色。这个基因的等位基因变异与自闭症和成瘾易感性有关。可变剪接导致多个转录变异体,编码不同的异构体。[由RefSeq,2008年7月提供]
Related ID:
NCBI:4897
ENSEMBL:ENSG00000091129
HGNC:7994
UNIPROT:Q92823
OMIM:601581
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4897
102
33
309072 bp
143.89
74
2
9
13
NRCAM Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
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Interactions
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Regulation
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Residues
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
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Journal
Year
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