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中文人类
NRAS - NRAS Proto-oncogene, GTPase
Alias:
NS6
CMNS
KRAS
NCMS
ALPS4
N-ras
NRAS1
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这是一种N-ras癌基因，编码在高尔基体和质膜之间穿梭的膜蛋白。这种穿梭是通过棕榈酰化和解棕榈酰化来调节的，由ZDHHC9-GOLGA7复合体完成。编码的蛋白具有内在的GTP酶活性，由鸟苷酸交换因子激活，并由GTP酶激活蛋白失活。该基因的突变与体细胞直肠癌症、滤泡性甲状腺癌症、自身免疫性淋巴增生综合症、Noonan综合症和幼年髓细胞性白血病有关。[RefSeq提供，2011年6月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NRAS Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
