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中文人类
NPM1 - Nucleophosmin 1
Alias:
B23
NPM
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这个基因编码的蛋白质参与几个细胞过程，包括中心体复制、蛋白质伴侣和细胞增殖。编码的磷酸蛋白在核仁、核和细胞质之间穿梭，将核糖体蛋白质和核心组蛋白从核输送到细胞质。这个蛋白质还被发现能将肿瘤抑制因子ARF与核仁隔离，防止其降解，直到需要时为止。这个基因的突变与急性粒细胞白血病有关。已经发现了这个基因的几十种假基因。[RefSeq，2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NPM1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
