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中文人类
NPY - Neuropeptide Y
Alias:
PYY4
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这种基因编码一种在中枢神经系统中广泛表达的神经肽，影响许多生理过程，包括皮质兴奋性、应激反应、食物摄入、昼夜节律和心血管功能。神经肽通过G蛋白偶联受体抑制腺苷酸环化酶，激活有丝分裂原激活的蛋白激酶（MAPK），调节细胞内钙水平，并激活钾通道。该基因中的多态性导致信号肽中的亮氨酸7变为脯氨酸，与胆固醇水平升高、饮酒量增加有关，可能是各种代谢和心血管疾病的危险因素。该蛋白质还展示了对抗细菌和真菌的抗菌活性。[RefSeq，2014年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NPY Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
