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中文人类
NFX1 - Nuclear Transcription Factor, X-box Binding 1
Alias:
NFX2
Tex42
TEG-42
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MHC II类基因表达主要受转录因子调控，这些因子结合到X和Y盒子上，这是MHC II类基因近端启动子中高度保守的两个元素。这个基因编码的蛋白质是一种能够结合HLA-DRA和其他MHC II类基因的保守X盒基序的转录抑制因子。该蛋白质可能通过限制II类MHC分子被IFN-γ诱导的时间来调节炎症反应的持续时间。已经发现了三种可变剪接变体，每种变体编码不同的异构体。[RefSeq,2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NFX1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
