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中文人类
NEK3 - NIMA Related Kinase 3
Alias:
HSPK36
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这个基因编码NimA(永不在有丝分裂A)家族的一员，该家族是丝氨酸/苏氨酸蛋白激酶。编码的蛋白质与其他NimA家族成员不同，它不受细胞周期的调节，主要存在于细胞质中。激酶被催乳素刺激激活，导致VAV2鸟苷酸交换因子、paxillin的磷酸化和RAC1 GTP酶的激活。人类已经发现了两个这个基因的功能等位基因。参考基因组装配(GRCh38)代表一个功能等位基因，与缺乏外显子的替代功能等位基因相比，它与蛋白质编码转录本中额外编码外显子的包含相关联。[由RefSeq，2019年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NEK3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
