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中文人类
ACLY - ATP Citrate Lyase
Alias:
ACL
ATPCL
CLATP
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ATP柠檬酸裂解酶是许多组织中负责细胞质乙酰辅酶A合成的主要酶。该酶是四聚体（相对分子质量约为440,000），由明显相同的亚基组成。它催化柠檬酸和辅酶A形成乙酰辅酶A和草酰乙酸，同时伴随ATP水解为ADP和磷酸根。产物乙酰辅酶A用于几个重要的生物合成途径，包括脂肪生成和胆固醇生成。在神经组织中，ATP柠檬酸裂解酶可能涉及乙酰胆碱的生物合成。已经发现了这个基因的多个转录变异体，编码不同的异构体。[RefSeq提供，2014年12月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ACLY Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
