人类

ATF4 - Activating Transcription Factor 4

Alias:
CREB2
TXREB
CREB-2
TAXREB67
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种转录因子,最初被鉴定为广泛表达的哺乳动物DNA结合蛋白,可以结合HTLV-1的LTR中的tax响应增强子元件。编码的蛋白质也被分离并鉴定为cAMP响应元件结合蛋白2(CREB-2)。这个基因编码的蛋白质属于一个DNA结合蛋白家族,包括AP-1家族转录因子、cAMP响应元件结合蛋白(CREBs)和CREB样蛋白质。这些转录因子共享一个涉及蛋白质之间相互作用的亮氨酸拉链区域,位于一个基本氨基酸区段的C端,该区域作为DNA结合结构域发挥作用。已经描述了编码相同蛋白质的两个可变转录本。两个假基因位于X染色体上的q28区域,该区域包含一个大倒位复制。[RefSeq,2011年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
3
2128 bp
38.59
32
--
12
29

ATF4 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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