Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
NAB2 - NGFI-A Binding Protein 2
Alias:
MADER
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个NGFI-A结合(NAB)蛋白家族的成员,这些蛋白在细胞核中发挥作用,抑制由一些EGR(早期生长反应)转激活子家族成员诱导的转录。NAB蛋白可以通过保守的N-末端结构域与其他EGR或NAB蛋白同源或异源多聚化,并通过两个部分冗余的C-末端结构域抑制转录。编码蛋白的转录抑制部分是通过与核小体重塑和去乙酰化(NuRD)复合物的相互作用实现的。已经描述了可变剪接的转录本变异体,但其生物学有效性尚未确定。[由RefSeq,2008年7月提供]
Related ID:
NCBI:4665
ENSEMBL:ENSG00000166886
HGNC:7627
UNIPROT:Q15742
OMIM:602381
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4665
2
7
6363 bp
56.59
16
1
5
13
NAB2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top