人类

NAB2 - NGFI-A Binding Protein 2

Alias:
MADER
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个NGFI-A结合(NAB)蛋白家族的成员,这些蛋白在细胞核中发挥作用,抑制由一些EGR(早期生长反应)转激活子家族成员诱导的转录。NAB蛋白可以通过保守的N-末端结构域与其他EGR或NAB蛋白同源或异源多聚化,并通过两个部分冗余的C-末端结构域抑制转录。编码蛋白的转录抑制部分是通过与核小体重塑和去乙酰化(NuRD)复合物的相互作用实现的。已经描述了可变剪接的转录本变异体,但其生物学有效性尚未确定。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
7
6363 bp
56.59
16
1
5
13

NAB2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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