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中文人类
GADD45B - Growth Arrest And DNA Damage Inducible Beta
Alias:
MYD118
GADD45BETA
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这个基因属于一组基因，这些基因的转录水平在压力生长停滞条件和DNA损伤剂处理后增加。这组基因通过调节p38/JNK途径的激活来响应环境压力。这种激活是通过其蛋白质结合并激活MTK1/MEKK4激酶来介导的，MTK1/MEKK4激酶是p38和JNK MAPKs的上游激活子。这些基因或其蛋白质产物的功能涉及生长和凋亡的调节。这些基因受到不同机制的调节，但它们通常协调表达并协同作用以抑制细胞生长。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GADD45B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
