Log In|Sign Up
中文人类
MYD88 - MYD88 Innate Immune Signal Transduction Adaptor
Alias:
WM1
IMD68
MYD88D
Favorite
这个基因编码一个细胞质适配蛋白，在天然和适应性免疫反应中扮演重要角色。这个蛋白作为白细胞介素-1和Toll样受体信号通路中的必需信号转导子发挥作用。这些通路调节众多促炎基因的激活。编码的蛋白由一个N-末端死亡结构域和一个C-末端Toll-白细胞介素1受体结构域组成。这个基因有缺陷的患者对细菌性感染易感性增加。交替剪接产生多个转录变异体。[RefSeq，2010年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MYD88 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
