人类

MYCN - MYCN Proto-oncogene, BHLH Transcription Factor

Alias:
NMYC
ODED
MODED
N-myc
bHLHe37
MYCNsORF
MYCNsPEP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是MYC家族的成员,编码一个具有碱性螺旋-环-螺旋(bHLH)结构域的蛋白质。这个蛋白质位于细胞核中,必须与另一个bHLH蛋白质二聚化以结合DNA。这个基因的扩增与各种肿瘤,尤其是神经母细胞瘤有关。已经发现这个基因有多种可变剪接转录变异体,编码不同的异构体。[由RefSeq,2014年6月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
3
6455 bp
49.56
187
4
17
16

MYCN Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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