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中文人类
MYC - MYC Proto-oncogene, BHLH Transcription Factor
Alias:
MRTL
MYCC
c-Myc
bHLHe39
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这个基因是一个原癌基因，编码一个在细胞周期进展、凋亡和细胞转化中起作用的核磷酸蛋白。编码的蛋白质与相关的转录因子MAX形成异二聚体。这个复合物结合E盒DNA共识序列，并调控特定目标基因的转录。这个基因的扩增在多种人类癌症中频繁观察到。涉及这个基因的易位与人类患者的伯基特淋巴瘤和多发性骨髓瘤有关。有证据表明，翻译从上游的帧内非AUG(CUG)起始位点和下游的AUG起始位点开始，从而产生具有不同N端的两类不同异构体。[RefSeq,2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MYC Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
