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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MTIF2 - Mitochondrial Translational Initiation Factor 2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
在蛋白质生物合成起始过程中,起始因子-2(IF-2)以GTP依赖的方式促进起始tRNA与核糖体小亚基的结合。原核IF-2是一个单条多肽,而真核细胞质IF-2(eIF-2)是一个三聚体蛋白。牛肝线粒体含有IF-2(mt),这是一种85kD的单体蛋白,相当于原核IF-2。预测的727个氨基酸的人蛋白含有29个氨基酸的预序列。人类IF-2(mt)与酵母IF-2(mt)和几种原核IF-2的氨基酸序列一致性为32-38%,蛋白质中G结构域的保守性最高。[RefSeq,2016年3月提供]
Related ID:
NCBI:4528
ENSEMBL:ENSG00000085760
HGNC:7441
UNIPROT:P46199
OMIM:603766
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4528
22
16
32654 bp
81.32
34
--
2
6
MTIF2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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