人类

MTIF2 - Mitochondrial Translational Initiation Factor 2

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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
在蛋白质生物合成起始过程中,起始因子-2(IF-2)以GTP依赖的方式促进起始tRNA与核糖体小亚基的结合。原核IF-2是一个单条多肽,而真核细胞质IF-2(eIF-2)是一个三聚体蛋白。牛肝线粒体含有IF-2(mt),这是一种85kD的单体蛋白,相当于原核IF-2。预测的727个氨基酸的人蛋白含有29个氨基酸的预序列。人类IF-2(mt)与酵母IF-2(mt)和几种原核IF-2的氨基酸序列一致性为32-38%,蛋白质中G结构域的保守性最高。[RefSeq,2016年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
22
16
32654 bp
81.32
34
--
2
6

MTIF2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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