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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MT2A - Metallothionein 2A
Alias:
MT2
MT-2
MT-II
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是金属硫蛋白家族的一员。这个基因家族编码的蛋白质分子量较低,富含半胱氨酸,缺乏芳香族残基,并能结合二价重金属离子,改变细胞内重金属的浓度。这些蛋白质作为抗氧化剂,保护免受羟基自由基的损害,对细胞内金属的稳态控制非常重要,并在重金属的解毒中发挥作用。编码的蛋白质在某些细胞类型中与同源盒包含1基因编码的蛋白质相互作用,控制细胞内锌水平,影响凋亡和自噬途径。这个基因中的一些多态性与癌症风险增加相关。[RefSeq,2017年9月提供]
Related ID:
NCBI:4502
ENSEMBL:ENSG00000125148
HGNC:7406
UNIPROT:P02795
OMIM:156360
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4502
1
3
914 bp
6.04
2
--
6
11
MT2A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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