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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MST1R - Macrophage Stimulating 1 Receptor
Alias:
RON
SEA
PTK8
CD136
NPCA3
CDw136
p185-Ron
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个具有酪氨酸激酶活性的细胞表面受体,可以识别巨噬细胞刺激蛋白(MSP)。这个蛋白质的成熟形式是由二硫键连接的α和β亚基异源二聚体组成,通过蛋白水解切割单链前体生成。在MSP的刺激下,β亚基会发生酪氨酸磷酸化。这个蛋白质在肺部的粘液纤毛传输装置的纤毛上皮中表达,并与MSP一起被认为参与宿主防御。可变剪接产生多种转录变异体,编码可能经历相似蛋白水解加工的不同异构体。[由RefSeq,2016年1月提供]
Related ID:
NCBI:4486
ENSEMBL:ENSG00000164078
HGNC:7381
UNIPROT:Q04912
OMIM:600168
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4486
29
20
16872 bp
152.24
69
1
8
24
MST1R Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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Transcript
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No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Name
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CAS Number
Status
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References Literature
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No Data Found!
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