Log In|Sign Up
中文人类
MSH4 - MutS Homolog 4
Alias:
ASG
POF20
SPGF2
Favorite
这个基因编码DNA错配修复mutS家族的一员。这个成员是一种有丝分裂特异性的蛋白质，不参与DNA错配的纠正，但对于互逆转换和减数分裂I期同源染色体的正确分离是必需的。这种蛋白质与MSH5形成独特的异源二聚体，可以特异性地结合到Holliday连接及其发育前体，从而引发ADP-ATP交换，并在减数分裂双链断裂修复过程中稳定亲本染色体之间的相互作用。[由RefSeq，2011年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MSH4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
