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中文人类
MSH3 - MutS Homolog 3
Alias:
DUP
FAP4
MRP1
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这个基因编码的蛋白质与MSH2形成异源二聚体，形成MutS beta，是复制后DNA错配修复系统的一部分。MutS beta通过结合错配位点并开始与MutL alpha异源二聚体形成复合物来启动错配修复。这个基因在第一个外显子中包含一个多态性9 bp重复序列。该重复序列在参考基因组序列中出现了6次，已经报道的重复次数为3-7次。这个基因的缺陷是导致子宫内膜癌易感性的原因之一。[RefSeq，2011年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MSH3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
