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中文人类
EIF2AK4 - Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4
Alias:
GCN2
PVOD2
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这个基因编码一个激酶家族成员，该家族可以磷酸化真核翻译起始因子-2（EIF2）的alpha亚基，导致蛋白质合成的下调。编码的蛋白质通过结合不带电荷的转移RNA来响应氨基酸缺乏。它也可能在葡萄糖缺乏和病毒感染时被激活。这个基因的突变已经在患有常染色体隐性肺静脉闭塞性疾病-2的患者中发现。[由RefSeq，2014年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
EIF2AK4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
