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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Otulin - OTU deubiquitinase with linear linkage specificity
Alias:
m3Sapc
Fam105b
m7-1Sapc
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
硫依赖性去泛素酶。参与几个过程,包括负调控NF-kappaB转录因子活性;蛋白质线性去泛素化;以及信号传导的调控。位于细胞质中。是LUBAC复合物的一部分。在几个结构中表达,包括鳃弓;心血管系统;生殖泌尿系统;肠道;和血淋巴系统。这个基因的人类同源物与otulipenia有关。与人类OTULIN(具有线性连接特性的OTU去泛素酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:432940
ENSEMBL:ENSMUSG00000046034
UNIPROT:Q3UCV8
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
432940
6
8
24789 bp
40.32
13
6
Otulin Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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