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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Adcy1 - adenylate cyclase 1
Alias:
AC1
brl
I-AC
D11Bwg1392e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活腺苷酸环化酶活性。参与几个过程,包括化学突触传递的调节;神经炎性反应;以及CREB转录因子活性的正向调节。在轴突生成和长期记忆的上游或内发挥作用。位于细胞质;谷氨酸能突触;以及突触后密度。在Schaffer collateral - CA1突触和海马蓬毛纤维到CA3突触中活跃。是突触后密度膜的集成组件。在包括消化系统;生殖泌尿系统;神经系统;呼吸系统;和感觉器官在内的几个结构中表达。这个基因的人类同源物与常染色体隐性非综合征性耳聋44有关。与人类ADCY1(腺苷酸环化酶1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:432530
ENSEMBL:ENSMUSG00000020431
UNIPROT:O88444
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
432530
1
20
115074 bp
123.37
9
6
Adcy1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
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* This data comes from NCBI.
Gene Expression
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