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中文人类
ASGR1 - Asialoglycoprotein Receptor 1
Alias:
HL-1
ASGPR
ASGPR1
CLEC4H1
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这个基因编码一种asialoglycoprotein受体的亚基。这个受体是一种跨膜蛋白，在血清糖蛋白稳态中扮演关键角色，通过介导具有暴露的末端半乳糖或N-乙酰半乳糖胺残基的糖蛋白的内吞作用和溶酶体降解。asialoglycoprotein受体可能促进多种病毒包括乙型肝炎的肝内感染，也是肝脏特异性的药物传递的靶点。asialoglycoprotein受体是一种异源寡聚蛋白，由主要和次要亚基组成，这些亚基由不同的基因编码。这个基因编码的蛋白质是更丰富的主要亚基。已经观察到这个基因的替代剪接转录变体编码多种异构体。[RefSeq，2011年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ASGR1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
