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中文人类
MMP8 - Matrix Metallopeptidase 8
Alias:
HNC
CLG1
MMP-8
PMNL-CL
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这个基因编码基质金属蛋白酶（MMP）家族的一员。这些蛋白质参与胚胎发育、繁殖和组织重塑中的细胞外基质的分解，以及疾病过程，如关节炎和转移。该蛋白质不同位点的蛋白水解导致具有不同N-末端的多种活性形式的酶。该蛋白质在I型、II型和III型胶原的降解中发挥作用。该基因是定位到染色体11q22.3的MMP基因簇的一部分。可选的剪接导致多个转录变异体。[由RefSeq，2015年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MMP8 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
