人类

MMP7 - Matrix Metallopeptidase 7

Alias:
MMP-7
MPSL1
PUMP-1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码肽酶M10家族的成员,该家族成员参与正常生理过程中细胞外基质的分解,如胚胎发育、繁殖和组织重塑,以及疾病过程中,如关节炎和转移。编码的前原原蛋白在蛋白水解过程中被加工成成熟的蛋白酶。这种分泌的蛋白酶分解蛋白聚糖、纤维连接蛋白、弹性蛋白和酪蛋白,并且与大多数MMP家族成员不同,它缺乏保守的C端血红蛋白域。该酶参与伤口愈合,并在小鼠中的研究表明,它调节肠道黏膜中防御素的活动。该基因是染色体11上MMP基因簇的一部分。该基因在多种人类癌症中表现出升高的表达水平。[RefSeq,2016年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
6
10240 bp
29.68
14
--
4
7

MMP7 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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