人类

AFDN - Afadin, Adherens Junction Formation Factor

Alias:
AF6
MLLT4
MLL-AF6
l-afadin
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个多结构域蛋白质,参与胚胎发育过程中细胞连接的信号传递和组织。它还已被鉴定为急性淋巴细胞白血病(ALL-1)基因的融合伙伴,涉及具有t(6;11)(q27;q23)易位的急性髓细胞白血病。已经描述了这个基因的替代剪接转录变异体,编码不同的异构体,然而并非所有变异体都已完全特征化。[由RefSeq提供,2011年5月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
53
34
145460 bp
206.80
16
--
9
20

AFDN Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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