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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MAP3K10 - Mitogen-activated Protein Kinase Kinase Kinase 10
Alias:
MST
MLK2
MEKK10
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是丝氨酸/苏氨酸激酶家族的一员。这个激酶已被证明可以激活MAPK8/JNK和MKK4/SEK1,并且这个激酶本身可以被磷酸化,从而被JNK激酶激活。这个激酶在JNK信号通路中优先发挥作用,据报道,它涉及神经生长因子(NGF)诱导的神经元凋亡。[由RefSeq,2008年7月提供]
Related ID:
NCBI:4294
ENSEMBL:ENSG00000130758
HGNC:6849
UNIPROT:Q02779
OMIM:600137
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4294
5
10
24150 bp
103.69
50
--
6
6
MAP3K10 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
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Residues
Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
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Journal
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IF
No Data Found!
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