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中文人类
MAP3K1 - Mitogen-activated Protein Kinase Kinase Kinase 1
Alias:
MEKK
MEKK1
SRXY6
MEKK 1
MAPKKK1
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这个基因编码的蛋白质是一种丝氨酸/苏氨酸激酶，并参与一些信号传导级联，包括ERK和JNK激酶途径以及NF-kappa-B途径。该编码蛋白质通过自磷酸化激活，并需要镁作为磷酸化其他蛋白质的辅因子。该蛋白质在其N-末端具有植物同源域（PHD）赋予的E3连接酶活性，并在其C-末端具有激酶结构域赋予的激酶活性。[由RefSeq，2012年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MAP3K1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
