人类

MCL1 - MCL1 Apoptosis Regulator, BCL2 Family Member

Alias:
TM
EAT
MCL1L
MCL1S
Mcl-1
BCL2L3
MCL1-ES
bcl2-L-3
mcl1/EAT
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种抗凋亡蛋白,属于Bcl-2家族成员。可变剪接产生多种转录子变异体。最长的基因产物(同种型1)通过抑制凋亡来增强细胞生存能力,而其他剪接变异的较短基因产物(同种型2和同种型3)促进凋亡并诱导死亡。[RefSeq, 2010年10月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
3
5053 bp
37.34
12
--
10
26

MCL1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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