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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MCL1 - MCL1 Apoptosis Regulator, BCL2 Family Member
Alias:
TM
EAT
MCL1L
MCL1S
Mcl-1
BCL2L3
MCL1-ES
bcl2-L-3
mcl1/EAT
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种抗凋亡蛋白,属于Bcl-2家族成员。可变剪接产生多种转录子变异体。最长的基因产物(同种型1)通过抑制凋亡来增强细胞生存能力,而其他剪接变异的较短基因产物(同种型2和同种型3)促进凋亡并诱导死亡。[RefSeq, 2010年10月提供]
Related ID:
NCBI:4170
ENSEMBL:ENSG00000143384
HGNC:6943
UNIPROT:Q07820
OMIM:159552
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4170
3
3
5053 bp
37.34
12
--
10
26
MCL1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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