人类

MAP4 - Microtubule Associated Protein 4

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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种主要的非神经元微管相关蛋白。这种蛋白质含有一个与神经元微管相关蛋白(MAP2)和微管相关蛋白tau(MAPT/TAU)的微管结合结构域相似的结构域。这种蛋白质促进微管组装,并已显示可以抵消有丝分裂微管崩溃促进的不稳定化。发现细胞周期蛋白B与这种蛋白质相互作用,将细胞分裂周期2(CDC2)激酶靶向到微管。这种蛋白质的磷酸化影响微管特性和细胞周期进程。已发现这个基因的多个转录变异体编码不同的异构体。[RefSeq,2008年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
167
21
238154 bp
121.00
56
--
5
32

MAP4 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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