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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ARRB1 - Arrestin Beta 1
Alias:
ARB1
ARR1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
逮捕蛋白/β-逮捕蛋白家族成员被认为参与G蛋白偶联受体的激动剂介导的脱敏作用,并导致对刺激(如激素、神经递质或感知信号)的细胞反应的具体抑制。逮捕蛋白β1是一种胞质蛋白,作为β-肾上腺素受体激酶(BARK)介导的β-肾上腺素受体脱敏的辅助因子。除了中枢神经系统外,它在外周血白细胞中高表达,因此BARK/β-逮捕蛋白系统被认为在调节受体介导的免疫功能中起主要作用。已经描述了编码不同逮捕蛋白β1异构体的可变剪接转录本。[由RefSeq,2011年1月提供]
Related ID:
NCBI:408
ENSEMBL:ENSG00000137486
HGNC:711
UNIPROT:P49407
OMIM:107940
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
408
9
16
91540 bp
47.07
10
--
8
41
ARRB1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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