人类

NBR1 - NBR1 Autophagy Cargo Receptor

Alias:
IAI3B
M17S2
MIG19
1A1-3B
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质最初被鉴定为卵巢癌中监测的卵巢肿瘤抗原。编码的蛋白质含有B-box/coiled-coil基序,存在于许多具有转化潜力的基因中。它通过与非泛素化自噬底物形成细胞内包涵体,作为过氧化物酶体选择性的自噬降解的特异性自噬受体发挥作用。这个基因位于17号染色体的一个区域,靠近BRCA1肿瘤抑制基因。这个基因的可变剪接导致多个转录变异体。[RefSeq,2014年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9
21
41280 bp
107.41
45
--
8
20

NBR1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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