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中文人类
EPCAM - Epithelial Cell Adhesion Molecule
Alias:
ESA
KSA
M4S1
MK-1
DIAR5
EGP-2
EGP40
KS1/4
MIC18
TROP1
BerEp4
EGP314
HNPCC8
LYNCH8
MOC-31
Ber-Ep4
TACSTD1
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这个基因编码一种与癌症相关的抗原，并属于至少包括两个I型膜蛋白的家族。这个抗原在大多数正常上皮细胞和胃肠道癌上表达，并作为同型钙非依赖细胞粘附分子发挥作用。该抗原被用作人类癌症免疫治疗治疗的靶点。这个基因的突变导致先天性绒毛性肠炎。[由RefSeq，2008年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
EPCAM Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
