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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
LTB - Lymphotoxin Beta
Alias:
p33
TNFC
TNFSF3
TNLG1C
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
淋巴毒素β是TNF家族的一种II型膜蛋白。它通过异源三聚体的形成将淋巴毒素α锚定在细胞表面。在淋巴细胞表面的主要形式是淋巴毒素α1/β2复合物(例如1个分子α/2个分子β),该复合物是淋巴毒素β受体的主要配体。次要复合物是淋巴毒素α2/β1。LTB是炎症反应系统的诱导剂,并涉及淋巴组织的正常发育。淋巴毒素β异构体b无法与淋巴毒素α复合,表明淋巴毒素β独立于淋巴毒素α的功能。可变剪接产生多种编码不同异构体的转录变异体。[由RefSeq,2008年7月提供]
Related ID:
NCBI:4050
ENSEMBL:ENSG00000227507
HGNC:6711
UNIPROT:Q06643
OMIM:600978
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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Reference
4050
2
4
1868 bp
25.39
3
--
11
8
LTB Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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